What About the Girls? Sex-Based Differences in Autistic Traits and Adaptive Skills.

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TitleWhat About the Girls? Sex-Based Differences in Autistic Traits and Adaptive Skills.
Publication TypeJournal Article
Year of Publication2018
AuthorsRatto, AB, Kenworthy, L, Yerys, BE, Bascom, J, Wieckowski, ATrubanova, White, SW, Wallace, GL, Pugliese, C, Schultz, RT, Ollendick, TH, Scarpa, A, Seese, S, Register-Brown, K, Martin, A, Anthony, LGutermuth
JournalJ Autism Dev Disord
Date Published2018 05
KeywordsAdaptation, Psychological, Adolescent, Autism Spectrum Disorder, Case-Control Studies, Child, Female, Humans, Intellectual Disability, Male, Parents, Sex Characteristics, Surveys and Questionnaires

There is growing evidence of a camouflaging effect among females with autism spectrum disorder (ASD), particularly among those without intellectual disability, which may affect performance on gold-standard diagnostic measures. This study utilized an age- and IQ-matched sample of school-aged youth (n = 228) diagnosed with ASD to assess sex differences on the ADOS and ADI-R, parent-reported autistic traits, and adaptive skills. Although females and males were rated similarly on gold-standard diagnostic measures overall, females with higher IQs were less likely to meet criteria on the ADI-R. Females were also found to be significantly more impaired on parent reported autistic traits and adaptive skills. Overall, the findings suggest that some autistic females may be missed by current diagnostic procedures.

Alternate JournalJ Autism Dev Disord
PubMed ID29204929
PubMed Central IDPMC5925757
Grant ListP30 HD040677 / HD / NICHD NIH HHS / United States
IDDRC P30 HD040677 / / Children's National Health Institute / International
RC1 MH088791 / MH / NIMH NIH HHS / United States
R03 HD081070 / HD / NICHD NIH HHS / United States
U54 HD086984 / HD / NICHD NIH HHS / United States
R03HD081070 / / National Institute for Child Health and Human Development / International