Potential Risk Factors for the Development of Self-Injurious Behavior among Infants at Risk for Autism Spectrum Disorder.

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TitlePotential Risk Factors for the Development of Self-Injurious Behavior among Infants at Risk for Autism Spectrum Disorder.
Publication TypeJournal Article
Year of Publication2017
AuthorsDimian, AF, Botteron, KN, Dager, SR, Elison, JT, Estes, AM, Pruett, JR, Schultz, RT, Zwaigenbaum, L, Piven, J, Wolff, JJ
Corporate AuthorsIBIS Network
JournalJ Autism Dev Disord
Volume47
Issue5
Pagination1403-1415
Date Published2017 05
ISSN1573-3432
KeywordsAutism Spectrum Disorder, Child Development, Child, Preschool, Developmental Disabilities, Female, Humans, Infant, Logistic Models, Longitudinal Studies, Male, Prevalence, Prospective Studies, Risk Factors, Self-Injurious Behavior
Abstract

Prevalence of self-injurious behavior (SIB) is as high as 50% among children with autism spectrum disorder (ASD). Identification of risk factors for the development of SIB is critical to early intervention and prevention. However, there is little empirical research utilizing a prospective design to identify early risk factors for SIB. The purpose of this study was to evaluate behavioral characteristics predicting SIB at age 2 years among 235 infants at high familial risk for ASD. Logistic regression results indicated that presence of SIB or proto-SIB and lower developmental functioning at age 12 months significantly predicted SIB at 24 months. A pattern of persistent SIB over this period was associated with a diagnosis of autism and poorer cognitive and adaptive outcomes.

DOI10.1007/s10803-017-3057-9
Alternate JournalJ Autism Dev Disord
PubMed ID28220358
PubMed Central IDPMC5385192
Grant ListU54 HD083091 / HD / NICHD NIH HHS / United States
P30 ES010126 / ES / NIEHS NIH HHS / United States
U54 HD087011 / HD / NICHD NIH HHS / United States
P30 HD003110 / HD / NICHD NIH HHS / United States
U54 HD086984 / HD / NICHD NIH HHS / United States
K01 MH101653 / MH / NIMH NIH HHS / United States