The modified checklist for autism in toddlers: a follow-up study investigating the early detection of autism spectrum disorders.

Registration Now Open for

ADOS-2 Clinical Training Workshop

November 25-27. Click here for info!

TitleThe modified checklist for autism in toddlers: a follow-up study investigating the early detection of autism spectrum disorders.
Publication TypeJournal Article
Year of Publication2008
AuthorsKleinman, JM, Robins, DL, Ventola, PE, Pandey, J, Boorstein, HC, Esser, EL, Wilson, LB, Rosenthal, MA, Sutera, S, Verbalis, AD, Barton, M, Hodgson, S, Green, J, Dumont-Mathieu, T, Volkmar, F, Chawarska, K, Klin, A, Fein, D
JournalJ Autism Dev Disord
Volume38
Issue5
Pagination827-39
Date Published2008 May
ISSN0162-3257
KeywordsAutistic Disorder, Child, Preschool, Early Diagnosis, Female, Follow-Up Studies, Humans, Male, Mass Screening, Surveys and Questionnaires
Abstract

Autism spectrum disorders (ASD) often go undetected in toddlers. The Modified Checklist for Autism in Toddlers (M-CHAT) was used to screen 3,793 children aged 16-30 months from low- and high-risk sources; screen positive cases were diagnostically evaluated. Rescreening was performed on 1,416 children aged 42-54 months. Time 1 Positive Predictive Value (PPV) was .36 for the initial screening and .74 for the screening plus follow-up telephone interview; values were similar for Time2 PPV. When separating referral sources, PPV was low for the low-risk sample but acceptable with the followup telephone interview. Children with ASD from the low-risk and high-risk samples were highly similar. Results indicate that the M-CHAT continues to be a promising instrument for the early detection of ASD.

DOI10.1007/s10803-007-0450-9
Alternate JournalJ Autism Dev Disord
PubMed ID17882539
PubMed Central IDPMC3612529
Grant ListR01 HD039961 / HD / NICHD NIH HHS / United States
R40 MC00270 / / PHS HHS / United States