Maturation of hemispheric specialization for face encoding during infancy and toddlerhood.

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TitleMaturation of hemispheric specialization for face encoding during infancy and toddlerhood.
Publication TypeJournal Article
Year of Publication2021
AuthorsChen, Y, Slinger, M, J Edgar, C, Bloy, L, Kuschner, ES, Kim, M, Green, HL, Chiang, T, Yount, T, Liu, S, Lebus, J, Lam, S, Stephen, JM, Huang, H, Roberts, TPL
JournalDev Cogn Neurosci
Volume48
Pagination100918
Date Published2021 04
ISSN1878-9307
KeywordsDominance, Cerebral, Face, Female, Humans, Infant, Magnetoencephalography, Male, Temporal Lobe
Abstract

Little is known about the neural processes associated with attending to social stimuli during infancy and toddlerhood. Using infant magnetoencephalography (MEG), fusiform gyrus (FFG) activity while processing Face and Non-Face stimuli was examined in 46 typically developing infants 3 to 24 months old (28 males). Several findings indicated FFG maturation throughout the first two years of life. First, right FFG responses to Face stimuli decreased as a function of age. Second, hemispheric specialization to the face stimuli developed somewhat slowly, with earlier right than left FFG peak activity most evident after 1 year of age. Right FFG activity to Face stimuli was of clinical interest, with an earlier right FFG response associated with better performance on tests assessing social and cognitive ability. Building on the above, clinical studies examining maturational change in FFG activity (e.g., lateralization and speed) in infants at-risk for childhood disorders associated with social deficits are of interest to identify atypical FFG maturation before a formal diagnosis is possible.

DOI10.1016/j.dcn.2021.100918
Alternate JournalDev Cogn Neurosci
PubMed ID33571846
PubMed Central IDPMC7876542
Grant ListR01 DC008871 / DC / NIDCD NIH HHS / United States
R01 MH107506 / MH / NIMH NIH HHS / United States
U54 HD086984 / HD / NICHD NIH HHS / United States
R01 HD093776 / HD / NICHD NIH HHS / United States
K01 MH108762 / MH / NIMH NIH HHS / United States
K01 MH108822 / MH / NIMH NIH HHS / United States
R01 MH092535 / MH / NIMH NIH HHS / United States