Driven: CAR's Science Blog

Boosting Social Behaviors in People with Autism
It may be possible to boost social interaction in people with autism by using a new therapeutic drug target, according to new research from the University of Pennsylvania and the Children's Hospital of Philadelphia. The research team conducted a study in mice to examine a whether a mutation in a specific gene, PCDH10, affects social behavior.  ...

Frankly, My Dear. That's Clear: An Expert Q&A on 'Frank' Presentations in Autism
Autism spectrum disorder (ASD) is so varied in its manifestation of behavioral and social differences that it is hard to make any blanket assumptions about any individual’s abilities, impairments, or interests based on that diagnosis. But one thing that a lot of individuals on the spectrum have in common is that their autism sometimes seems immediately obvious to clinicians who specialize in ASD when they meet them — even before they begin a diagnostic evaluation. ...

CAR Researcher Dreams of a Better Night's Sleep for Children With Autism, Their Families
Children and adolescents need a healthy sleep pattern to fully develop and to perform their best during the day, but – as many reading this know all to well- sleep difficulties plague as many as  50%-80% of children with autism spectrum disorder (ASD)- and by default, their parents!  ...

CHOP, Drexel Join National Consortium Studying Baby Teeth for Clues to Environmental, Chemical Risks Associated With Autism
Two Philadelphia research centers are among 10 centers studying baby teeth of high-risk children to learn about risk factors in the womb. ...

For youth struggling with social skills, treating anxiety could be key
We all feel anxiety in certain social situations every now and then, but for those with autism spectrum disorder (ASD), social anxiety can be the spark that starts a wildfire. ...

Categories:
Resources for Families and First Responders Following North Miami Shooting
At CAR, we have been following the news coverage of the disturbing incident late last week in North Miami in which a police officer shot the Charles Kinsey, the caregiver of a 26-year-old man with autism named Arnaldo Eliud Rios Soto ....

Huddle Up 2016 Scores a Touchdown!
We were incredibly lucky to have one of the most beautiful days of the spring for the 6th annual Huddle Up for Autism at Lincoln Financial Field! ...

New CHOP Research Study Tests Brain’s Response to Single Dose of Arbaclofen (STX209)
Many in the autism community are familiar with the trial drug STX209, also called arbaclofen, which affects a chemical system called GABA. In 2010, clinical trials were launched to evaluate whether arbaclofen might become the first medication to treat core symptoms of social communication impairment and repetitive behavior in autism spectrum disorder. ...

Switching Lenses: A Shift in Perspective Led Researchers to Unexpected Results About Face-Processing in ASD
Humanity seems to be “hard-wired” to pay attention to faces and facial expressions. Zeroing in on faces (rather than other body parts or objects) and being able to differentiate between people’s identities or expressions is one of the first skills developed during infancy. ...

Categories: Social Development
CHOP Researchers Identify Gene That Plays Important Role in Autism & Other Neuropsychiatric Conditions
A team of researchers led by Tara Wenger, PhD of The Children's Hospital of Philadelphia's Center for Autism Research (CAR) have found that genetic mutations in a specific family of genes – the “metabotropic glutamate receptors” (mGluRs) – play a significant role in a person’s risk for...