Diagnostic stability in very young children with autism spectrum disorders.

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TitleDiagnostic stability in very young children with autism spectrum disorders.
Publication TypeJournal Article
Year of Publication2008
AuthorsKleinman, JM, Ventola, PE, Pandey, J, Verbalis, AD, Barton, M, Hodgson, S, Green, J, Dumont-Mathieu, T, Robins, DL, Fein, D
JournalJ Autism Dev Disord
Date Published2008 Apr
KeywordsAutistic Disorder, Child, Child, Preschool, Diagnosis, Differential, Early Diagnosis, Female, Humans, Male, Prevalence, Severity of Illness Index

Autism Spectrum Disorders (ASD) diagnosis in very young children may be delayed due to doubts about validity. In this study, 77 children received a diagnostic and developmental evaluation between 16 and 35 months and also between 42 and 82 months. Diagnoses based on clinical judgment, Childhood Autism Rating Scale, and the Autism Diagnostic Observation Schedule were stable over time. Diagnoses made using the Autism Diagnostic Interview were slightly less stable. According to clinical judgment, 15 children (19%) moved off the autism spectrum by the second evaluation; none moved onto the spectrum. Results indicate diagnostic stability at acceptable levels for diagnoses made at age 2. Movement off the spectrum may reflect true improvement based on maturation, intervention, or over-diagnosis at age 2.

Alternate JournalJ Autism Dev Disord
PubMed ID17924183
PubMed Central IDPMC3625643
Grant ListR01 HD039961 / HD / NICHD NIH HHS / United States
R01 HD 039961 / HD / NICHD NIH HHS / United States
R40 MC 00270 / / PHS HHS / United States