Autism spectrum disorder symptoms among children enrolled in the Study to Explore Early Development (SEED).

New CAR Research Sheds Light on

 

Universal Screening for Autism in Toddlers

TitleAutism spectrum disorder symptoms among children enrolled in the Study to Explore Early Development (SEED).
Publication TypeJournal Article
Year of Publication2015
AuthorsWiggins, LD, Levy, SE, Daniels, J, Schieve, L, Croen, LA, DiGuiseppi, C, Blaskey, L, Giarelli, E, Lee, L-C, Pinto-Martin, J, Reynolds, A, Rice, C, Rosenberg, CRobinson, Thompson, P, Yeargin-Allsopp, M, Young, L, Schendel, D
JournalJ Autism Dev Disord
Volume45
Issue10
Pagination3183-94
Date Published2015 Oct
ISSN1573-3432
KeywordsAutism Spectrum Disorder, Child, Child Development, Child, Preschool, Developmental Disabilities, Female, Humans, Male, Parents, Phenotype
Abstract

This study examined the phenotypic profiles of children aged 30-68 months in the Study to Explore Early Development (SEED). Children classified as autism spectrum disorder (ASD), developmental delay (DD) with ASD symptoms, DD without ASD symptoms, and population comparison (POP) differed significantly from each other on cognitive, adaptive, behavioral, and social functioning and the presence of parent-reported conditions. Children with ASD and DD with ASD symptoms had mild to severe ASD risk on several measures compared to children with other DD and POP who had little ASD risk across measures. We conclude that children in SEED have varying degrees of ASD impairment and associated deficits. SEED thus provides a valuable sample to explore ASD phenotypes and inform risk factor analyses.

DOI10.1007/s10803-015-2476-8
Alternate JournalJ Autism Dev Disord
PubMed ID26048040
PubMed Central IDPMC4573234
Grant ListU10 DD000180 / DD / NCBDD CDC HHS / United States
U10DD000184 / DD / NCBDD CDC HHS / United States
U10 DD000181 / DD / NCBDD CDC HHS / United States
U10DD000181 / DD / NCBDD CDC HHS / United States
U10 DD000184 / DD / NCBDD CDC HHS / United States
U01 DD001210 / DD / NCBDD CDC HHS / United States
P30 ES013508 / ES / NIEHS NIH HHS / United States
U01 DD000498 / DD / NCBDD CDC HHS / United States
CC999999 / / Intramural CDC HHS / United States
U10DD000182 / DD / NCBDD CDC HHS / United States
U10 DD000182 / DD / NCBDD CDC HHS / United States
U10DD000498 / DD / NCBDD CDC HHS / United States
U10DD000183 / DD / NCBDD CDC HHS / United States
U10 DD000183 / DD / NCBDD CDC HHS / United States
U10DD000180 / DD / NCBDD CDC HHS / United States
Comments
Leave a Comment