Autism spectrum disorder screening with the CBCL/1½-5: Findings for young children at high risk for autism spectrum disorder.

New CAR Research Sheds Light on

 

Universal Screening for Autism in Toddlers

TitleAutism spectrum disorder screening with the CBCL/1½-5: Findings for young children at high risk for autism spectrum disorder.
Publication TypeJournal Article
Year of Publication2019
AuthorsRescorla, LA, Winder-Patel, BM, Paterson, SJ, Pandey, J, Wolff, JJ, Schultz, RT, Piven, J
JournalAutism
Volume23
Issue1
Pagination29-38
Date Published2019 Jan
ISSN1461-7005
Abstract

The screening power of the CBCL/1½-5's Withdrawn and -Pervasive Developmental Problems (DSM-PDP) scales to identify children diagnosed with autism spectrum disorder at 24 months was tested in a longitudinal, familial high-risk study. Participants were 56 children at high risk for autism spectrum disorder due to an affected older sibling (high-risk group) and 26 low-risk children with a typically developing older sibling (low-risk group). At 24 months, 13 of the 56 high-risk children were diagnosed with autism spectrum disorder, whereas the other 43 were not. The high-risk children diagnosed with autism spectrum disorder group had significantly higher scores on the CBCL/1½-5's -Pervasive Developmental Problems and Withdrawn scales than children in the low-risk and high-risk children not diagnosed with autism spectrum disorder groups . Receiver operating characteristic analyses yielded very high area under the curve values (0.91 and 0.89), and a cut point of  ⩾ 60 yielded sensitivity of 77% and specificity of 97% to 99% between the high-risk children diagnosed with autism spectrum disorder and the combination of low-risk and high-risk children not diagnosed with autism spectrum disorder. Consistent with several previous studies, the CBCL/1½-5's -Pervasive Developmental Problems scale and the Withdrawn syndrome differentiated well between children diagnosed with autism spectrum disorder and those not diagnosed.

DOI10.1177/1362361317718482
Alternate JournalAutism
PubMed ID28931307
PubMed Central IDPMC6756982
Grant ListR01 HD055741 / HD / NICHD NIH HHS / United States
U54 HD086984 / HD / NICHD NIH HHS / United States